ReDisulphID

a tool for identifying drug-targetable redox-active disulphides

MYND-type zinc finger-containing chromatin reader ZMYND8

Intramolecular
Cysteine 1046 and cysteine 1050
A redox-regulated disulphide may form within MYND-type zinc finger-containing chromatin reader ZMYND8 between cysteines 1046 and 1050 (1096 and 1100 respectively in this structure).

Details

Redox score ?
78
PDB code
5mq4
Structure name
crystal structure of the leucine zipper of human prkcbp1
Structure deposition date
2016-12-20
Thiol separation (Å)
4
Half-sphere exposure sum ?
60
Minimum pKa ?
9
% buried
16
Peptide accession
Q9ULU4
Residue number A
1046
Residue number B
1050
Peptide name
MYND-type zinc finger-containing chromatin reader ZMYND8

Ligandability

Cysteine 1046 of MYND-type zinc finger-containing chromatin reader ZMYND8

Cysteine 1050 of MYND-type zinc finger-containing chromatin reader ZMYND8

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